{"id":7466,"date":"2025-12-22T10:21:48","date_gmt":"2025-12-22T09:21:48","guid":{"rendered":"https:\/\/www.pjpharma.it\/?p=7466"},"modified":"2026-04-10T10:29:57","modified_gmt":"2026-04-10T09:29:57","slug":"reflucalm-clinical-study-on-adult-acid-reflux","status":"publish","type":"post","link":"https:\/\/www.pjpharma.it\/en\/reflucalm-clinical-study-on-adult-acid-reflux\/","title":{"rendered":"Reflucalm: Clinical Study on Adult Acid Reflux"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>Reflucalm: Clinical Study on Adult Gastroesophageal Reflux Disease (GERD)<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal conditions worldwide, affecting a large portion of the adult population. Symptoms such as heartburn, acid regurgitation, chest pain, and digestive discomfort can significantly impair quality of life. In this context, the medical device&nbsp;<strong>Reflucalm<\/strong>&nbsp;offers a rapid-acting solution to relieve GERD symptoms thanks to its protective formulation for the esophageal mucosa.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Clinical Study on Reflucalm: Methodology and Results in Adult Patients<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Gruppo FarmaImpresa<\/strong>&nbsp;conducted a multicenter observational clinical study involving 20 adult patients experiencing symptoms of gastroesophageal reflux. The treatment lasted 4 weeks, and patients were assessed both before (T0) and after (T1) administration using the validated&nbsp;<strong>GERD-HRQL<\/strong>&nbsp;questionnaire (Gastroesophageal Reflux Disease \u2013 Health-Related Quality of Life).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The&nbsp;<strong>GERD-HRQL<\/strong>&nbsp;is a globally recognized clinical tool designed to assess the impact of GERD on patients\u2019 quality of life, measuring symptom severity, frequency, and functional impairment.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Study Results: Marked Symptom Improvement<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">After 4 weeks of Reflucalm treatment, clinical data showed a significant improvement in the GERD-HRQL score. The average score dropped from 33.9 to 3.4, with a reduction of 30.5 points (<strong>p &lt; 0.001<\/strong>).<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.pjpharma.it\/wp-content\/uploads\/2026\/04\/download-11.webp\"><img decoding=\"async\" src=\"https:\/\/www.pjpharma.it\/wp-content\/uploads\/2026\/04\/download-11-1024x640.webp\" alt=\"\" class=\"wp-image-7464\"\/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Clinical Effectiveness in Adults: Acid Reflux Symptoms Drastically Reduced<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>100%<\/strong>\u00a0of patients experienced a clinically significant improvement (\u226516-point reduction)<\/li>\n\n\n\n<li><strong>25%<\/strong>\u00a0achieved complete symptom remission<\/li>\n\n\n\n<li><strong>Treatment satisfaction<\/strong>\u00a0rose from 0% to 85%, highlighting both tolerability and efficacy<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Why Choose Reflucalm for Adult Reflux?<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Reflucalm offers an effective, natural, and well-tolerated solution for GERD symptoms. It works by protecting the esophageal lining and promoting digestive well-being without adverse effects.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Indications:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><em>Gastroesophageal reflux disease (GERD)<\/em><\/li>\n\n\n\n<li><em>Heartburn, acid regurgitation, burning sensation<\/em><\/li>\n\n\n\n<li><em>Frequent digestive discomfort<\/em><\/li>\n<\/ul>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><strong>Looking for a B2B-ready or private label solution?<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">We are certified manufacturers of medical devices, dietary supplements, and cosmetics.&nbsp;<strong>Reflucalm<\/strong>&nbsp;is ready for market entry or private labeling, with full regulatory and clinical support.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-fe48e5de wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"mailto:info@farmaimpresa.it\"><strong>Contact Us<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gruppo FarmaImpresa conducted a multicenter observational clinical study in adult patients affected by gastroesophageal reflux disease (GERD) to evaluate the effectiveness of Reflucalm, a medical device designed to protect the esophageal mucosa. After 4 weeks of treatment, results showed a statistically significant reduction in symptoms, assessed using the validated GERD-HRQL questionnaire, with a marked improvement in quality of life.<\/p>\n","protected":false},"author":2,"featured_media":7465,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[412],"tags":[2139,2137,2138,2140,2118,2143,2141,2054,2125,2142,2144],"class_list":["post-7466","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-clinical-studies","tag-acid-reflux-symptoms","tag-adult-patients","tag-clinical-data","tag-clinical-effectiveness","tag-clinical-support","tag-gastroesophageal-reflux-disease","tag-gerd-hrql-questionnaire","tag-observational-clinical-study","tag-reflusso-gastroesofageo","tag-reflux-in-adults","tag-symptoms-of-gastroesophageal-reflux"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Reflucalm: Clinical Study on Adult Acid Reflux<\/title>\n<meta name=\"description\" content=\"Discover Reflucalm, a clinically tested medical device for managing gastroesophageal reflux in adults. 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